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Healthcare practitioners do not recommend using GLP-1s for PMOS if you are pregnant or trying to conceive
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The only persistent side effect was appetite suppression, which is the intended therapeutic outcome
improving safety profiles with prodrug constructs that functionalize the C-3 hydroxyl group with hydrophilic moieties (e.g., like PEG/amino acids), expand therapeutic windows, e.g., prodrug derivatives that increase HepG2 IC 50 from 22.5 M to 58.3 M (Tao et al., 2015)
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